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ea0073oc10.6 | Oral Communications 10: Thyroid | ECE2021

Impact of allogeneic stem cell transplantation on thyroid function

Felicetti Francesco , Zavattaro Marco , Faraci Danilo , Gatti Filippo , Dellacasa Chiara , Busca Alessandro , Arvat Emanuela , Rosso Daniela , Marinelli Lorenzo , Margherita Dionisi-Vici , Giaccone Luisa , Bruno Benedetto , Brignardello Enrico

IntroductionPrimary hypothyroidism, which is one of the main endocrine complications of allogenic stem cells transplantation (allo-SCT), has been largely studied in children. Conversely, data on adults are still limited with a reported incidence widely ranging between 9 and 47%. Older age, multiple allo-SCT, chronic Graft vs Host Disease (cGVHD), prolonged immunosuppressive therapy and high-dose total body irradiation (TBI) have been indicated as potenti...

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ea0063p674 | Pituitary and Neuroendocrinology 2 | ECE2019

First and second day cortisol levels as predictors of long-term hypocortisolism after pituitary surgery

Prencipe Nunzia , Gasco Valentina , Gatti Filippo , Caputo Marina , D'Angelo Valentina , Bona Chiara , Caprino Mirko Parasiliti , Berton Alessandro Maria , Cambria Valeria , Penner Federica , Giordano Roberta , Ghigo Ezio , Zenga Francesco , Grottoli Silvia

Introduction: Prediction of HPA (hypothalamus-pituitary-adrenal) activity after trans-sphenoidal pituitary surgery (NS) is essential for post-operative management. There is not unique behavior in this setting: most of specialists suggests 4-6 weeks of glucocorticoid supplementation and treatment interruption after demonstration of normal endogenous response. Some authors suggest early cortisol detection for the identification of patients requiring glucocorticoid therapy. Aim o...

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Endocrine Abstracts

Impact of allogeneic stem cell transplantation on thyroid function

First and second day cortisol levels as predictors of long-term hypocortisolism after pituitary surgery

BiosciAbstracts